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2015, doi: 10.3109/14647273.2015.1050462

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Geriatric Use In elderly patients, it is recommended that the dosage be limited to the smallest effective amount to preclude the development of ataxia or oversedation (2 mg to 2.5 mg once or twice daily, initially to be increased gradually as needed and tolerated)

In peptide research, it is one of the single most useful numbers to know, because it directly influences dosing frequency in animal models, experimental timing, and the interpretation of pharmacodynamic results

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